UBE2D2 antibody (C-Term)

Catalog No. ABIN5534799

The Rabbit Polyclonal anti-UBE2D2 antibody has been validated for WB. It is suitable to detect UBE2D2 in samples from Human.

Quick Overview for UBE2D2 antibody (C-Term) (ABIN5534799)

Target: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2D2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBE2D2 Antibody

Binding Specificity: AA 112-140, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBE2D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the C-terminal region of human UBE2D2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UBE2D2

Target: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Alternative Name: UBE2D2

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Molecular Weight: 17 kDa

Gene ID: 7322

UniProt: P62837

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades